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地特胰岛素/Insulin Detemir

 

地特胰岛素

Insulin Detemir

 

地特胰岛素为长效基础胰岛素类似物,活性贴近人体自身胰岛素,可改善 1 型、2 型糖尿病引发的高血糖。地特胰岛素是人胰岛素 B 链去掉 30 位苏氨酸,B29 位赖氨酸连接14 碳脂肪酸侧链。分子经结构修饰改造,皮下注射后释放平缓,药效平稳持续 24 小时。产品依托大肠杆菌表达体系制备,纯度优异,无动物源杂质,用药安全性良好,低血糖发生率低,也不易引发体重增加

Insulin Detemir is a long-acting basal insulin analog with activity closely resembling that of endogenous human insulin, which improves hyperglycemia caused by type 1 and type 2 diabetes mellitus. Insulin detemir is produced by removing threonine at position 30 of the B chain of human insulin and linking a 14-carbon fatty acid side chain to lysine at position B29. Through structural modification, the molecule exhibits a slow release profile after subcutaneous injection, providing smooth and sustained efficacy for 24 hours. The product is manufactured using an E. coli expression system, achieving excellent purity and freedom from animal-derived impurities. It offers a favorable safety profile, with a low incidence of hypoglycemia and a low tendency to cause weight gain.

 

产品特性 Product Features

 

地特胰岛素(Insulin Detemir)

CAS CAS Number 169148-63-4
分子式 Molecular Formula C₂₆₇H₄₀₂N₆₄O₇₆S₆
分子量 Molecular Weight 5916.89 g/mol
来源 Source 大肠杆菌 Escherichia coli 
纯度 Purity 99%
用途 Use  同德谷胰岛素 Insulin Degludec

 

 

 

产品优势 Product Advantages

内毒素含量极低 ·无动物源性,不含动物来源原料,质量稳定,质量数据齐全

纯度高:微生物、宿主蛋白、金属离子等的残留低于生物制品限度要求

Animal-free, containing no animal-derived raw materials, with stable quality and comprehensive quality data.

High purity: Residual levels of microorganisms, host cell proteins, metal ions, etc., are below the limit requirements for biological products.

 

储存条件 Storage Conditions

冻干粉-25~-15℃保存。

Store the lyophilized powder at -25 °C to -15 °C.

 

产品规格 Product Specification

提供各规格的产品,从克级、公斤级、吨级皆可,接受客户产品定制,为客户提供系统解决方案

可提供配套制剂技术。

111We offer products in various specifications, from gram, kilogram to metric ton levels. Customization is accepted, and we provide systematic solutions for our clients. Supporting formulation technology is also available.

 

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